Tratamento das Hiperidroses com a Toxina Botulinica tipo A: Artigo de revisão

Abstract

BACKGROUND: Hyperhidrosis is characterized by excessive sweating of the forehead, hands, feet, and armpits, either alone or in combination. It affects about one percent of the population. This study aimed to observe the effects of botulinum toxin in patients with hyperhidrosis and demonstrates the application technique of botulinum toxin, the areas of incidence of the disease, and the duration of the results.

METHODS: A retrospective analysis the patients with primary hyperhidrosis treated with botulinum toxin type A, between July 2000 and July 2010. A total of 135 areas were treated, of which the most prevalent is the axillary, followed by the palms and soles. Treatment consisted of intradermal injections of botulinum toxin. The total dose applied ranged from 37.5 U to 150 U, with an average dose of 75 U for each treated area.

RESULTS: The therapeutic effect of botulinum toxin was observed from the third day after treatment, with a 50 percent reduction in symptoms within the first week of treatment and up to 94 percent reduction in the number of hyperhidrosis events after the second week. The reduction of symptoms lasted, on average, for 7 months. No cases of mortality were observed.

CONCLUSIONS: The treatment of primary hyperhidrosis with type A botulinum toxin, although temporary, is an effective, safe, and minimally invasive treatment option. It has a high degree of satisfaction and allows patients to return to their professional activities on the same day. Side effects and complications are temporary, infrequent, and regress without sequelae.